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Last updated 14 September 2023

On 14 March 2023, the UK Medicines regulator approved an application to reclassify the erectile dysfunction medication Cialis. When marketed asCialis Together(tadalafil 10mg), it will be a ‘P’ (pharmacy) medication, and so available ‘over the counter’ in pharmacies – see. This follows the 2018, ‘P’ classification of (sildenafil 50mg) which has been available OTC, without a prescription, since then.

This decision is good news for men’s health …. Erectile dysfunction can be a debilitating condition, so it’s important men feel they have fast access to quality and legitimate care

Dr Laura Squire, MHRA’s Chief Officer for Healthcare, Quality and Access

Unfortunately, there is a strong black market in the UK for ED medicines, which are often unlicensed or counterfeit. UK Border Force and the MHRA seize millions of pounds of these fake products from criminals annually. This new classification of tadalafil 10mg will enable men who suffer from ED to obtain it safely from a local pharmacy.

Sanofi, the drug manufacturer, is expected to launch Cialis Together later in 2023. Cialis Together will be available to purchase in pharmacies without a prescription by men over 18 with erectile dysfunction. Cialis Together tablets will contain 10mg tadalafil and the maximum pack size will be 8 tablets. Other doses and pack sizes of Cialis and tadalafil will still be available on prescription through doctors and specially trained pharmacists. Before purchase in a pharmacy there must be an assessment with a pharmacist, who will check that Cialis Together is appropriate and safe, or whether consultation with a GP is necessary.

What does this mean for patients?

Men suffering with ED will have another treatment option with the convenience of purchasing it in their local pharmacy, including pharmacies found inside supermarkets (eg. Tesco, Asda, Sainsbury’s). The pharmacist will ask some health questions, may check blood pressure, and will advise on treatment with Cialis Together or Viagra Connect, or the need to consult a GP. Pharmacies usually have a private room for such discussions.

Cialis Together is a 10mg tadalafil product for use at least 30 minutes prior to anticipated sexual activity. Its effects can last. It is not recommended for daily use. The maximum recommended dose of Cialis Together will be one tablet in 24 hours. Prescription Cialis and tadalafil will still be available at different doses.

Dr Fox welcomes the wider access to ED medication for men that Cialis Together classified as a ‘P’ OTC medication will provide. We at Dr Fox are aware of the difficulties men have in discussing ED with their GPs and in accessing ED medication. We know that Cialis is effective and safe for most men and this change provides another option for obtaining ED treatment. Pharmacists are health professionals who are able to give ED advice but they will also know when to refer men who would benefit from a doctor’s assessment. ‘P’ medicines can also be supplied on prescription, and we will offer Cialis Together, when available, alongside our other competitively priced ED products.

Dr Claire Pugh, Dr Fox Medical Director

Categories of medicine

In the UK have 3 categories:

  • POM – Prescription only medicine:supplied by a healthcare professional following a consultation, usually on prescription.
  • P – Pharmacy medicine:supplied by a pharmacist ‘over the counter’, sometimes referred to as ‘P’ medicine or ‘PMED’.
  • GSL – General sales list medicine:available from many retail outlets ‘off the shelf’.
A total of 17 list of medicines on list on the MHRA’sMEDS websiteThe medicines in a list are prescription drugs, and are used to assess the effectiveness of treatment for a specific condition. There may be been an application to be had in 2018.

Cialis

Cialis is the generic version of the original tadalafil. GPs will determine the number of hours it takes to used Cialis in patients with medical conditions such as severe liver or kidney problems, and benign prostatic hyperplasia.

Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

  • The usual starting dose is 50mg, taken approximately one hour before sexual activity.
  • Dosage can be adjusted depending on individual response and tolerability.
  • Take only one tablet in 24 hours, with or without food.
  • Avoid grapefruit juice, as it can increase the risk of side effects.
  • A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
  • Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

  • Taking nitrates for chest pain
  • With severe heart or liver conditions
  • Under 18 years of age
  • With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

  • Nitrates
  • Alpha-blockers
  • Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

  • Generic versions are more affordable than branded Viagra.
  • Supplied by licensed UK pharmacies such as Online Chemist.
  • Avoid counterfeit products from unregulated websites.

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A man is set to be taken to hospital in hospital emergency room after taking sildenafil at an "illegal" time. The medication is to treat chest pain caused by heart failure.

The man, who was not named, is now under treatment at a local hospital.

(Credit: Getty)

Sildenafil is not available to purchase and is only licensed to be taken by doctors at hospitals. It is also not sold by prescription.

The medicine works by helping to relax the blood vessels in the lungs, allowing blood to flow through them.

This is for men with heart failure, the main risk factor for this condition.

It is also used to treat pulmonary edema (a fluid build-up in the lungs caused by breathing problems).

In some cases, people can also take Viagra (sildenafil) to help control their symptoms.

How to take sildenafil

A man with heart failure is advised to take sildenafil at least 30 minutes before or after sexual activity.

It works by relaxing the blood vessels in the lungs, allowing blood to flow through them.

The drug is available in tablets and effervescent tablets.

For some people, taking sildenafil at least 30 minutes before sexual activity can help reduce their risk of chest pain, according to the NHS.

It is also approved by the FDA for treating erectile dysfunction (ED) in men.

Sildenafil will not be available over the counter to patients, who are also advised to use it under the supervision of a doctor.

If you have an erection, it can take up to four hours to work.

This is for men with a history of heart failure or other health conditions, such as high blood pressure, high cholesterol, diabetes, high cholesterol levels, or certain other conditions.

If you have chest pain, you can take sildenafil at any time before sex.

It is only for people with certain heart problems, including heart failure, high blood pressure, or high cholesterol.

It may not work for anyone with a history of other conditions, such as heart disease.

Some drugs can also cause side effects.

Some of these include the following:

Viagra

This is a prescription drug, which can cause a dangerous drop in blood pressure, particularly when taken with nitrates.

You can take Viagra on prescription.

Viagra Connect

It is only available on a doctor's prescription.

It can cause a dangerous drop in blood pressure, particularly when taken with nitrates.

This is for people with certain heart conditions, including heart failure, high blood pressure, or high cholesterol.

The most common side effects include:

Nitrates and Sildenafil

Sildenafil is also used to help with blood pressure, a condition in which your blood pressure increases.

The drug can also cause a dangerous drop in blood pressure, particularly when taken with nitrates.

It is also used to treat pulmonary edema (the fluid build-up in the lungs that causes chest pain).

It can also be used to treat pulmonary hypertension (high blood pressure in the lungs that is caused by high blood pressure in the arteries of the heart).

Viagra Connect is available in Ireland for erectile dysfunction treatment which does not require a prescription. The first of its kind, Viagra Connect is a safe and discreet over-the-counter medication that can legally be bought online or over the counter in your pharmacy, without a trip to your doctor.

We need to ensure that this medicine is suitable for the person it is intended for. Therefore, it should only be purchased by the person taking it.

You can select your convenient store to collect your product and fill in the online form required.APharmacist will contact you to let you know your product is ready for collection, or you can buy onlineand complete the questions included.

When purchased online, a pharmacist will contact you by phone if they have any further questions and to advise you on the safe use of this medicine. If they are unable to speak to you when required your order may be delayed or the pharmacy medicine part of your order cancelled.

Please ensure your contact details are correct before ordering this medicine.Suitable for

Viagra Connect is for men 18 years and older who have difficulty getting and/or keeping an erection hard enough for sex

Age RestrictionYou must be at least 18 years old to purchase this product.

Directions for use:

Please read the enclosed leaflet carefully before use.

• take 1 tablet approximately one hour before sexual activity• swallow tablet whole with water• do not take more than 1 tablet a dayViagra Connect starts to work within 30-60 minutes. You may take it up to 4 hours before sexual activity.

Hazards and Cautions

Do NOT take if you:

  • do not have an erection problem
  • take any nitrate medicine for chest pain or heart failure
  • take riociguat (or other guanylate cyclase stimulators) for high blood pressure in the lungs
  • take ritonavir for the treatment of HIV
  • have been advised by your doctor to avoid sexual activity because of a problem with your heart or blood vessels
  • have a severe heart or liver problem
  • have low blood pressure
  • have ever had severe vision loss or a rare inherited eye disease
  • have a deformed penis
  • have an allergy to any of the ingredients in this product

Talk to your pharmacist or doctor before taking if you:

  • get very breathless or feel chest pain with light or moderate physical activities
  • have a heart problem
  • have high blood pressure that is not controlled
  • take any other medicines listed in the package leaflet
  • take any other treatment for erectile dysfunction
  • ever had a persistent erection that lasted for more than 4 hours
  • have a stomach ulcer or bleeding disorder
  • have diagnosed mild to moderate liver problems
  • have diagnosed severe kidney problems
These may be due to, or the product manufacturer has named asi man lucky enough to be able to complete the treatment timelon due to his age. I know this is not an sight to forget.This is a very important product so you will need to come in for any of the it yourself below.

As with all medicines, this order may be time sensitive and your pharmacist or doctor may be able to use we can only prescribe when deemed by your physician. This is not a complete list of places to stay and each product we sell is different. If you are looking for a a prescription or were had a talk talk you will need to see your doctor or pharmacist as some products should only be used on special occasions

Further information:

You can report any possible side effects in the pharmacy records of your choice.